A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model

CVA6 is one of Enteroviruses causing worldwide epidemics of HFMD with neurological and systemic complications. A suitable animal model is necessary for studying the pathogenesis of CVA6 and evaluating antiviral and vaccine efficacy. In this study, we generated a mouse-adapted CVA6 strain that succes...

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Detalles Bibliográficos
Autores principales: Li, Dong, Sun, Tiantian, Tao, Ling, Ji, Wangquan, Zhu, Peiyu, Liang, Ruonan, Zhang, Yu, Chen, Shuaiyin, Yang, Haiyan, Jin, Yuefei, Duan, Guangcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518251/
https://www.ncbi.nlm.nih.gov/pubmed/36036059
http://dx.doi.org/10.1080/22221751.2022.2119166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518251/
https://www.ncbi.nlm.nih.gov/pubmed/36036059
http://dx.doi.org/10.1080/22221751.2022.2119166

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