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A mouse-adapted CVA6 strain exhibits neurotropism and triggers systemic manifestations in a novel murine model
CVA6 is one of Enteroviruses causing worldwide epidemics of HFMD with neurological and systemic complications. A suitable animal model is necessary for studying the pathogenesis of CVA6 and evaluating antiviral and vaccine efficacy. In this study, we generated a mouse-adapted CVA6 strain that succes...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518251/ https://www.ncbi.nlm.nih.gov/pubmed/36036059 http://dx.doi.org/10.1080/22221751.2022.2119166 |