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Design, synthesis and evaluation of novel small molecules acting as Keap1-Nrf2 protein-protein interaction inhibitors

Direct interference with Kelch-like ECH-associated protein 1 (Keap1)-Nrf2 protein-protein interaction (PPI) has recently been introduced as an attractive approach to control life-threatening diseases like myocarditis. The present study aimed to investigate the potential application in myocarditis of...

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Detalles Bibliográficos
Autores principales: Sun, Yunfeng, Zheng, Lulu, Yang, Bo, Ge, Shuyu, Li, Qiang, Zhang, Mingwan, Shen, Shenghui, Ying, Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518255/
https://www.ncbi.nlm.nih.gov/pubmed/36128875
http://dx.doi.org/10.1080/14756366.2022.2124408