Design and synthesis of new trimethoxylphenyl-linked combretastatin analogues loaded on diamond nanoparticles as a panel for ameliorated solubility and antiproliferative activity

A new series of vinyl amide-, imidazolone-, and triazinone-linked combretastatin A-4 analogues have been designed and synthesised. These compounds have been evaluated for their cytotoxic activity against MDA-MB-231 breast cancer cells. The triazinone-linked combretastatin analogues (6 and 12) exhibi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zaki, Islam, Moustafa, Amal M. Y., Beshay, Botros Y., Masoud, Reham E., Elbastawesy, Mohammed A. I., Abourehab, Mohammed A. S., Zakaria, Mohamed Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518609/
https://www.ncbi.nlm.nih.gov/pubmed/36154552
http://dx.doi.org/10.1080/14756366.2022.2116016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518609/
https://www.ncbi.nlm.nih.gov/pubmed/36154552
http://dx.doi.org/10.1080/14756366.2022.2116016

Ejemplares similares