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No association of GABRA1 rs2279020 and GABRA6 rs3219151 polymorphisms with risk of epilepsy and antiepileptic drug responsiveness in Asian and Arabic populations: Evidence from a meta-analysis with trial sequential analysis

The γ-aminobutyric acid type A receptors (GABA(A)R) have been reported to contribute to the pathogenesis of epilepsy and the recurrence of chronic seizures. Genetic polymorphisms in GABRA1 and GABRA6 may confer a high risk of epilepsy and multiple drug resistance, but with conflicting results. We ai...

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Detalles Bibliográficos
Autores principales: Zhang, Tiejun, Yang, Yi, Sima, Xiutian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518753/
https://www.ncbi.nlm.nih.gov/pubmed/36188399
http://dx.doi.org/10.3389/fneur.2022.996631