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Emergence of qualitative states in synthetic circuits driven by ultrasensitive growth feedback

The mutual interactions between the synthetic gene circuits and the host growth could cause unexpected outcomes in the dynamical behaviors of the circuits. However, how the steady states and the stabilities of the gene circuits are affected by host cell growth is not fully understood. Here, we devel...

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Detalles Bibliográficos
Autores principales: Melendez-Alvarez, Juan Ramon, Tian, Xiao-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518899/
https://www.ncbi.nlm.nih.gov/pubmed/36112667
http://dx.doi.org/10.1371/journal.pcbi.1010518