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Type I interferon induces cancer stem cells-mediated chemotherapy resistance
In a recent study in Nature Immunology, Musella et al. demonstrate that suboptimal type I interferon (IFN-I) signaling in tumors undergoing immunogenic cell death (ICD) facilitates the accumulation of cancer stem cells (CSCs) by triggering the epigenetic regulator lysine demethylase 1B (KDM1B). KDM1...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Taylor & Francis
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518997/ https://www.ncbi.nlm.nih.gov/pubmed/36185803 http://dx.doi.org/10.1080/2162402X.2022.2127274 |