Cargando…

Type I interferon induces cancer stem cells-mediated chemotherapy resistance

In a recent study in Nature Immunology, Musella et al. demonstrate that suboptimal type I interferon (IFN-I) signaling in tumors undergoing immunogenic cell death (ICD) facilitates the accumulation of cancer stem cells (CSCs) by triggering the epigenetic regulator lysine demethylase 1B (KDM1B). KDM1...

Descripción completa

Detalles Bibliográficos
Autores principales: De Martino, Mara, Vanpouille-Box, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518997/
https://www.ncbi.nlm.nih.gov/pubmed/36185803
http://dx.doi.org/10.1080/2162402X.2022.2127274