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Type I interferon induces cancer stem cells-mediated chemotherapy resistance

In a recent study in Nature Immunology, Musella et al. demonstrate that suboptimal type I interferon (IFN-I) signaling in tumors undergoing immunogenic cell death (ICD) facilitates the accumulation of cancer stem cells (CSCs) by triggering the epigenetic regulator lysine demethylase 1B (KDM1B). KDM1...

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Detalles Bibliográficos
Autores principales:	De Martino, Mara, Vanpouille-Box, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Commentary
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9518997/ https://www.ncbi.nlm.nih.gov/pubmed/36185803 http://dx.doi.org/10.1080/2162402X.2022.2127274

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