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Investigating protein–excipient interactions of a multivalent V(HH) therapeutic protein using NMR spectroscopy

Multispecific therapeutic proteins come in a variety of formats, including bi- and tri-specific antibodies, dual-variable domain antibodies, and CrossMabs. These multivalent proteins are engineered to interact with multiple therapeutic target proteins with high specificity. Multi-domain proteins can...

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Detalles Bibliográficos
Autores principales: Panchal, Jainik, Falk, Bradley T., Antochshuk, Valentyn, McCoy, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519013/
https://www.ncbi.nlm.nih.gov/pubmed/36166705
http://dx.doi.org/10.1080/19420862.2022.2124902