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Combined Shikonin-Loaded MPEG-PCL Micelles Inhibits Effective Transition of Endothelial-to-Mesenchymal Cells

INTRODUCTION: Shikonin is well known for its anti-inflammatory activity in cardiovascular diseases. However, the application of shikonin is limited by its low water solubility and poor bioavailability. Methoxy poly (ethylene glycol)-b-poly (ε-caprolactone) (MPEG-PCL) is considered a promising delive...

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Detalles Bibliográficos
Autores principales: Li, Guanglin, Shang, Chenxu, Li, Qingqing, Chen, Lifang, Yue, Zejun, Ren, Lingxuan, Yang, Jianjun, Zhang, Jiye, Wang, Weirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519018/
https://www.ncbi.nlm.nih.gov/pubmed/36186533
http://dx.doi.org/10.2147/IJN.S374895