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Urinary T cells are detected in patients with immune checkpoint inhibitor-associated immune nephritis that are clonotypically identical to kidney T cell infiltrates

Acute kidney injury (AKI) occurs in ~20% of patients receiving immune checkpoint inhibitor (ICI) therapy; however, only 2–5% will develop ICI-mediated immune nephritis. Conventional tests are nonspecific in diagnosing disease pathology and invasive procedures (i.e. kidney biopsy) may not be feasible...

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Detalles Bibliográficos
Autores principales: Singh, Shailbala, Clemente, Leticia C., Parra, Edwin R., Tchakarov, Amanda, Yang, Chao, Li, Yisheng, Long, James P., Yee, Cassian, Lin, Jamie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519023/
https://www.ncbi.nlm.nih.gov/pubmed/36185804
http://dx.doi.org/10.1080/2162402X.2022.2124678