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Apyrase decreases phage induction and Shiga toxin release from E. coli O157:H7 and has a protective effect during infection

Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) cause gastrointestinal infection and, in severe cases, hemolytic uremic syndrome which may lead to death. There is, to-date, no therapy for this infection. Stx induces ATP release from host cells and ATP signaling mediates its cyt...

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Detalles Bibliográficos
Autores principales: Arvidsson, Ida, Tontanahal, Ashmita, Johansson, Karl, Kristoffersson, Ann-Charlotte, Kellnerová, Sára, Berger, Michael, Dobrindt, Ulrich, Karpman, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519026/
https://www.ncbi.nlm.nih.gov/pubmed/36138514
http://dx.doi.org/10.1080/19490976.2022.2122667