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The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity

RNA binding proteins and messenger RNAs (mRNAs) assemble into ribonucleoprotein granules that regulate mRNA trafficking, local translation, and turnover. The dysregulation of RNA-protein condensation disturbs synaptic plasticity and neuron survival and has been widely associated with human neurologi...

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Detalles Bibliográficos
Autores principales: Grzejda, Dominika, Mach, Jana, Schweizer, Johanna Aurelia, Hummel, Barbara, Rezansoff, Andrew Mischa, Eggenhofer, Florian, Panhale, Amol, Lalioti, Maria-Eleni, Cabezas Wallscheid, Nina, Backofen, Rolf, Felsenberg, Johannes, Hilgers, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519039/
https://www.ncbi.nlm.nih.gov/pubmed/36170367
http://dx.doi.org/10.1126/sciadv.abo5578