Sex-specific epigenetic development in the mouse hypothalamic arcuate nucleus pinpoints human genomic regions associated with body mass index

Recent genome-wide association studies corroborate classical research on developmental programming indicating that obesity is primarily a neurodevelopmental disease strongly influenced by nutrition during critical ontogenic windows. Epigenetic mechanisms regulate neurodevelopment; however, little is...

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Detalles Bibliográficos
Autores principales: MacKay, Harry, Gunasekara, Chathura J., Yam, Kit-Yi, Srisai, Dollada, Yalamanchili, Hari Krishna, Li, Yumei, Chen, Rui, Coarfa, Cristian, Waterland, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519050/
https://www.ncbi.nlm.nih.gov/pubmed/36170368
http://dx.doi.org/10.1126/sciadv.abo3991

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519050/
https://www.ncbi.nlm.nih.gov/pubmed/36170368
http://dx.doi.org/10.1126/sciadv.abo3991

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