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Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress

Diabetic nephropathy (DN) has become the most common secondary kidney disease causing end-stage renal disease (ESRD). Nevertheless, the underlying mechanisms responsible for DN remain largely unknown. Regulated in development and DNA damage response 1 (REDD1) is a prooxidative molecule known to cont...

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Detalles Bibliográficos
Autores principales: Mu, Lin, Chen, Nan, Chen, Yakun, Yang, Zhifen, Zhou, Huandi, Song, Shan, Shi, Yonghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519289/
https://www.ncbi.nlm.nih.gov/pubmed/36186658
http://dx.doi.org/10.1155/2022/6073911