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Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress
Diabetic nephropathy (DN) has become the most common secondary kidney disease causing end-stage renal disease (ESRD). Nevertheless, the underlying mechanisms responsible for DN remain largely unknown. Regulated in development and DNA damage response 1 (REDD1) is a prooxidative molecule known to cont...
Autores principales: | Mu, Lin, Chen, Nan, Chen, Yakun, Yang, Zhifen, Zhou, Huandi, Song, Shan, Shi, Yonghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519289/ https://www.ncbi.nlm.nih.gov/pubmed/36186658 http://dx.doi.org/10.1155/2022/6073911 |
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