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Eupalinolide O Induces Apoptosis in Human Triple-Negative Breast Cancer Cells via Modulating ROS Generation and Akt/p38 MAPK Signaling Pathway

BACKGROUND: Triple-negative breast cancer (TNBC) is a subtype of breast cancer with limited therapeutic options. Eupalinolide O (EO) was reported to inhibit tumor growth. This study is aimed at exploring the role of EO on TNBC both in vivo and in vitro. Methods. In in vitro experiments, 3-(4,5-dimet...

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Detalles Bibliográficos
Autores principales: Zhao, Yaping, Fu, Liping, Chen, Jinbai, Zhou, Junhao, Tian, Chongmei, Zhou, Daotang, Zhu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519309/
https://www.ncbi.nlm.nih.gov/pubmed/36185619
http://dx.doi.org/10.1155/2022/8802453