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LncRNA MDRL Mitigates Atherosclerosis through miR-361/SQSTM1/NLRP3 Signaling

OBJECTIVE: Long non-coding RNAs (lncRNAs) play many important roles in gene regulation and disease pathogenesis. Here, we sought to determine that mitochondrial dynamic related lncRNA (MDRL) modulates NLRP3 inflammasome activation and apoptosis of vascular smooth muscle cells (VSMCs) and protects ar...

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Detalles Bibliográficos
Autores principales: You, Ling, Zheng, Yanjie, Yang, Jing, Hou, Qian, Wang, Lianxia, Zhang, Yan, Zhao, Chunxia, Xie, Ruiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519314/
https://www.ncbi.nlm.nih.gov/pubmed/36186576
http://dx.doi.org/10.1155/2022/5463505