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Protein Kinase N2 Reduces Hydrogen Peroxide-inducedDamage and Apoptosis in PC12 Cells by AntiOxidative Stress and Activation of the mTOR Pathway
OBJECTIVE: To investigate the role and mechanism of protein kinase N2 (PKN2) in hydrogen peroxide (H(2)O(2))-induced injury of PC12 cells. METHOD: s. PC12 cells were transfected with lentivirus to knock down or overexpress PKN2 and then were treated with 300 μM H(2)O(2) to establish a cell model of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Hindawi
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519335/ https://www.ncbi.nlm.nih.gov/pubmed/36185087 http://dx.doi.org/10.1155/2022/2483669 |