Effect of Ketorolac on Pharmacokinetics and Pharmacodynamics of 5-Fluorouracil: In Vivo and In Vitro Study

BACKGROUND: This study aimed to evaluate the impact of ketorolac on the pharmacokinetics of 5-FU and its effect on the efficacy of 5-fluorouracil (5-FU) on the HT-29 cell line. METHODS: Cell culture: the HT-29 cell line was treated with different concentrations of 5-FU, ketorolac, and combination of...

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Detalles Bibliográficos
Autores principales: Atefinezhad, Motahare, Moghadamnia, Ahmadreza, Eftekhar, Seyed Parsa, Moghadamnia, Ali Akbar, Kazemi, Sohrab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519353/
https://www.ncbi.nlm.nih.gov/pubmed/36187458
http://dx.doi.org/10.1155/2022/5267861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519353/
https://www.ncbi.nlm.nih.gov/pubmed/36187458
http://dx.doi.org/10.1155/2022/5267861

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