A pathological link between dysregulated copper binding in Cu/Zn-superoxide dismutase and amyotrophic lateral sclerosis

Mutations in the gene coding Cu/Zn-superoxide dismutase (SOD1) are linked to a familial form of amyotrophic lateral sclerosis (ALS), and its pathological hallmark includes abnormal accumulation of mutant SOD1 proteins in spinal motorneurons. Mutant SOD1 proteins are considered to be susceptible to m...

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Detalles Bibliográficos
Autor principal: Furukawa, Yoshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2022
Materias:
Serial Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519421/
https://www.ncbi.nlm.nih.gov/pubmed/36213785
http://dx.doi.org/10.3164/jcbn.22-42

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519421/
https://www.ncbi.nlm.nih.gov/pubmed/36213785
http://dx.doi.org/10.3164/jcbn.22-42

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