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Structural interplay between DNA-shape protein recognition and supercoiling: The case of IHF
The integration host factor (IHF) is a prominent example of indirect readout as it imposes one of the strongest bends on relaxed linear DNA. However, the relation between IHF and torsionally constrained DNA, as occurs physiologically, remains unclear. By using atomistic molecular dynamics simulation...
Autores principales: | Watson, George D., Chan, Elliot W., Leake, Mark C., Noy, Agnes |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519438/ https://www.ncbi.nlm.nih.gov/pubmed/36212531 http://dx.doi.org/10.1016/j.csbj.2022.09.020 |
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