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A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome

The ancient, ongoing coevolutionary battle between bacteria and their viruses, bacteriophages, has given rise to sophisticated immune systems including restriction-modification and CRISPR-Cas. Many additional anti-phage systems have been identified using computational approaches based on genomic co-...

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Detalles Bibliográficos
Autores principales: Vassallo, Christopher N., Doering, Christopher R., Littlehale, Megan L., Teodoro, Gabriella I. C., Laub, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519451/
https://www.ncbi.nlm.nih.gov/pubmed/36123438
http://dx.doi.org/10.1038/s41564-022-01219-4