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A functional selection reveals previously undetected anti-phage defence systems in the E. coli pangenome
The ancient, ongoing coevolutionary battle between bacteria and their viruses, bacteriophages, has given rise to sophisticated immune systems including restriction-modification and CRISPR-Cas. Many additional anti-phage systems have been identified using computational approaches based on genomic co-...
Autores principales: | Vassallo, Christopher N., Doering, Christopher R., Littlehale, Megan L., Teodoro, Gabriella I. C., Laub, Michael T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519451/ https://www.ncbi.nlm.nih.gov/pubmed/36123438 http://dx.doi.org/10.1038/s41564-022-01219-4 |
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