SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope

Population antibody response is thought to be important in selection of virus variants. We report that SARS-CoV-2 infection elicits a population immune response that is mediated by a lineage of VH1-69 germline antibodies. A representative antibody R1-32 from this lineage was isolated. By cryo-EM, we...

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Detalles Bibliográficos
Autores principales: He, Ping, Liu, Banghui, Gao, Xijie, Yan, Qihong, Pei, Rongjuan, Sun, Jing, Chen, Qiuluan, Hou, Ruitian, Li, Zimu, Zhang, Yanjun, Zhao, Jincun, Sun, Hao, Feng, Bo, Wang, Qian, Yi, Haisu, Hu, Peiyu, Li, Pingchao, Zhang, Yudi, Chen, Zhilong, Niu, Xuefeng, Zhong, Xiaolin, Jin, Liang, Liu, Xiaofeng, Qu, Kun, Ciazynska, Katarzyna A., Carter, Andrew P., Briggs, John A. G., Chen, Jizheng, Liu, Jinsong, Chen, Xinwen, He, Jun, Chen, Ling, Xiong, Xiaoli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519457/
https://www.ncbi.nlm.nih.gov/pubmed/36151403
http://dx.doi.org/10.1038/s41564-022-01235-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519457/
https://www.ncbi.nlm.nih.gov/pubmed/36151403
http://dx.doi.org/10.1038/s41564-022-01235-4

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