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The hypothalamus-pituitary-adrenal axis in sepsis- and hyperinflammation-induced critical illness: Gaps in current knowledge and future translational research directions

The classical model of the vital increase in systemic glucocorticoid availability in response to sepsis- and hyperinflammation-induced critical illness is one of an activated hypothalamus-pituitary-adrenocortical axis. However, research performed in the last decade has challenged this rather simple...

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Detalles Bibliográficos
Autores principales: Van den Berghe, Greet, Téblick, Arno, Langouche, Lies, Gunst, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519475/
https://www.ncbi.nlm.nih.gov/pubmed/36162206
http://dx.doi.org/10.1016/j.ebiom.2022.104284