Non-canonical EphA2 activation underpins PTEN-mediated metastatic migration and poor clinical outcome in prostate cancer

BACKGROUND: The key process of mesenchymal to amoeboid transition (MAT), which enables prostate cancer (PCa) transendothelial migration and subsequent development of metastases in red bone marrow stroma, is driven by phosphorylation of EphA2(S897) by pAkt, which is induced by the omega-6 polyunsatur...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sachdeva, Ashwin, Hart, Claire A., Kim, Kyungmin, Tawadros, Thomas, Oliveira, Pedro, Shanks, Jonathan, Brown, Mick, Clarke, Noel
Μορφή: Online Άρθρο Κείμενο
Γλώσσα:English
Έκδοση: Nature Publishing Group UK 2022
Θέματα:
Article
Διαθέσιμο Online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519535/
https://www.ncbi.nlm.nih.gov/pubmed/35869144
http://dx.doi.org/10.1038/s41416-022-01914-3

Διαδίκτυο

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519535/
https://www.ncbi.nlm.nih.gov/pubmed/35869144
http://dx.doi.org/10.1038/s41416-022-01914-3

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