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Comprehensive multiplexed immune profiling of the ductal carcinoma in situ immune microenvironment regarding subsequent ipsilateral invasive breast cancer risk

BACKGROUND: Ductal carcinoma in situ (DCIS) is treated to prevent subsequent ipsilateral invasive breast cancer (iIBC). However, many DCIS lesions will never become invasive. To prevent overtreatment, we need to distinguish harmless from potentially hazardous DCIS. We investigated whether the immune...

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Detalles Bibliográficos
Autores principales: Almekinders, Mathilde M., Bismeijer, Tycho, Kumar, Tapsi, Yang, Fei, Thijssen, Bram, van der Linden, Rianne, van Rooijen, Charlotte, Vonk, Shiva, Sun, Baohua, Parra Cuentas, Edwin R., Wistuba, Ignacio I., Krishnamurthy, Savitri, Visser, Lindy L., Seignette, Iris M., Hofland, Ingrid, Sanders, Joyce, Broeks, Annegien, Love, Jason K., Menegaz, Brian, Wessels, Lodewyk, Thompson, Alastair M., de Visser, Karin E., Hooijberg, Erik, Lips, Esther, Futreal, Andrew, Wesseling, Jelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519539/
https://www.ncbi.nlm.nih.gov/pubmed/35768550
http://dx.doi.org/10.1038/s41416-022-01888-2