TrkC, a novel prognostic marker, induces and maintains cell survival and metastatic dissemination of Ewing sarcoma by inhibiting EWSR1-FLI1 degradation

Upregulation of EWSR1-FLI1 expression has been associated with invasiveness, induced cell survival, metastatic dissemination, and acquisition of self-renewal traits in Ewing sarcoma (ES). Although existing evidence implies that TrkC expression is linked to the pathogenesis of other cancer types, its...

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Detalles Bibliográficos
Autores principales: Kim, Min Soo, Lee, Won Sung, Lee, Hanki, Jin, Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519565/
https://www.ncbi.nlm.nih.gov/pubmed/36171207
http://dx.doi.org/10.1038/s41419-022-05275-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519565/
https://www.ncbi.nlm.nih.gov/pubmed/36171207
http://dx.doi.org/10.1038/s41419-022-05275-w

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