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Bivalent rotavirus VP4∗ stimulates protective antibodies against common genotypes of human rotaviruses
Non-replicating rotavirus vaccines are an alternative strategy to improve the efficacy and safety of rotavirus vaccines. The spike protein VP4, which could be enzymatically cleaved into VP8∗ and VP5∗, is an ideal target for the development of recombinant rotavirus vaccine. In our previous studies, w...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519587/ https://www.ncbi.nlm.nih.gov/pubmed/36185383 http://dx.doi.org/10.1016/j.isci.2022.105099 |