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Multiparameter analysis of timelapse imaging reveals kinetics of megakaryocytic erythroid progenitor clonal expansion and differentiation

Single-cell assays have enriched our understanding of hematopoiesis and, more generally, stem and progenitor cell biology. However, these single-end-point approaches provide only a static snapshot of the state of a cell. To observe and measure dynamic changes that may instruct cell fate, we develope...

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Detalles Bibliográficos
Autores principales: Scanlon, Vanessa M., Thompson, Evrett N., Lawton, Betty R., Kochugaeva, Maria, Ta, Kevinminh, Mayday, Madeline Y., Xavier-Ferrucio, Juliana, Kang, Elaine, Eskow, Nicole M., Lu, Yi-Chien, Kwon, Nayoung, Laumas, Anisha, Cenci, Matthew, Lawrence, Kalyani, Barden, Katie, Larsuel, Shannon T., Reed, Fiona E., Peña-Carmona, Gabriela, Ubbelohde, Ashley, Lee, June P., Boobalan, Shakthi, Oppong, Yvette, Anderson, Rachel, Maynard, Colby, Sahirul, Kaylie, Lajeune, Callista, Ivathraya, Varsha, Addy, Tiffany, Sanchez, Patricia, Holbrook, Colin, Van Ho, Andrew Tri, Duncan, James S., Blau, Helen M., Levchenko, Andre, Krause, Diane S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519589/
https://www.ncbi.nlm.nih.gov/pubmed/36171423
http://dx.doi.org/10.1038/s41598-022-19013-x