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Aptamer engineering exosomes loaded on biomimetic periosteum to promote angiogenesis and bone regeneration by targeting injured nerves via JNK3 MAPK pathway

Repairing critical bone defects is a complex problem in the clinic. The periosteum rich in nerve plays a vital role in initiating and regulating bone regeneration. However, current studies have paid little attention to repairing nerves in the periosteum to promote bone regeneration. Thus, it is esse...

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Detalles Bibliográficos
Autores principales: Su, Yanlin, Gao, Qing, Deng, Rongli, Zeng, Lian, Guo, Jingyi, Ye, Bing, Yu, Jialin, Guo, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519612/
https://www.ncbi.nlm.nih.gov/pubmed/36186848
http://dx.doi.org/10.1016/j.mtbio.2022.100434