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Loss of contact inhibition of locomotion in the absence of JAM-A promotes entotic cell engulfment

Entosis is a cell competition process during which tumor cells engulf other tumor cells. It is initiated by metabolic stress or by loss of matrix adhesion, and it provides the winning cell with resources derived from the internalized cell. Using micropatterns as substrates for single cell migration,...

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Detalles Bibliográficos
Autores principales: Schwietzer, Mariel F., Thölmann, Sonja, Kummer, Daniel, Kaschler, Anne, Greune, Lilo, Thüring, Eva-Maria, Schmidt, M. Alexander, Gerke, Volker, Ebnet, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519618/
https://www.ncbi.nlm.nih.gov/pubmed/36185363
http://dx.doi.org/10.1016/j.isci.2022.105144