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Inhibition of the pseudokinase MLKL alters extracellular vesicle release and reduces tumor growth in glioblastoma

Extracellular vesicles (EVs) are lipid-based nanosized particles that convey biological material from donor to recipient cells. EVs play key roles in glioblastoma progression because glioblastoma stem-like cells (GSCs) release pro-oncogenic, pro-angiogenic, and pro-inflammatory EVs. However, the mol...

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Detalles Bibliográficos
Autores principales: André-Grégoire, Gwennan, Maghe, Clément, Douanne, Tiphaine, Rosińska, Sara, Spinelli, Fiorella, Thys, An, Trillet, Kilian, Jacobs, Kathryn A., Ballu, Cyndie, Dupont, Aurélien, Lyne, Anne-Marie, Cavalli, Florence M.G., Busnelli, Ignacio, Hyenne, Vincent, Goetz, Jacky G., Bidère, Nicolas, Gavard, Julie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519628/
https://www.ncbi.nlm.nih.gov/pubmed/36185361
http://dx.doi.org/10.1016/j.isci.2022.105118