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Functional connectivity of the cortico-subcortical sensorimotor loop is modulated by the severity of nigrostriatal dopaminergic denervation in Parkinson’s Disease

To assess if the severity of nigrostriatal innervation loss affects the functional connectivity (FC) of the sensorimotor cortico-striato-thalamic-cortical loop (CSTCL) in Parkinson’s Disease (PD), Resting-State functional MRI and (18)F-DOPA PET data, simultaneously acquired on a hybrid PET/MRI scann...

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Detalles Bibliográficos
Autores principales: Quarantelli, Mario, Quattrone, Andrea, Sarica, Alessia, Cicone, Francesco, Cascini, Giuseppe Lucio, Quattrone, Aldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519637/
https://www.ncbi.nlm.nih.gov/pubmed/36171211
http://dx.doi.org/10.1038/s41531-022-00385-w