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Altered immunity to microbiota, B cell activation and depleted γδ/resident memory T cells in colorectal cancer

The role of microbiota:immune system dysregulation in the etiology of colorectal cancer (CRC) is poorly understood. CRC develops in gut epithelium, accompanied by low level inflammatory signaling, intestinal microbial dysbiosis and immune dysfunction. We examined populations of intraepithelial lymph...

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Detalles Bibliográficos
Autores principales: Noble, Alistair, Pring, Edward T., Durant, Lydia, Man, Ripple, Dilke, Stella M., Hoyles, Lesley, James, Steve A., Carding, Simon R., Jenkins, John T., Knight, Stella C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519644/
https://www.ncbi.nlm.nih.gov/pubmed/35316367
http://dx.doi.org/10.1007/s00262-021-03135-8