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Pseudotime analysis reveals novel regulatory factors for multigenic onset and monogenic transition of odorant receptor expression

During their maturation from horizontal basal stem cells, olfactory sensory neurons (OSNs) are known to select exactly one out of hundreds of olfactory receptors (ORs) and express it on their surface, a process called monogenic selection. Monogenic expression is preceded by a multigenic phase during...

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Detalles Bibliográficos
Autores principales: Hussainy, Mohammad, Korsching, Sigrun I., Tresch, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519747/
https://www.ncbi.nlm.nih.gov/pubmed/36171231
http://dx.doi.org/10.1038/s41598-022-20106-w