Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells

The transcription factor SNAI1 mediates epithelial-mesenchymal transition, fibroblast activation and controls inter-tissue migration. High SNAI1 expression characterizes metastatic triple-negative breast carcinomas, and its knockout by CRISPR/Cas9 uncovered an epithelio-mesenchymal phenotype accompa...

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Detalles Bibliográficos
Autores principales: Tsirigoti, Chrysoula, Ali, Mohamad Moustafa, Maturi, Varun, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519755/
https://www.ncbi.nlm.nih.gov/pubmed/36171192
http://dx.doi.org/10.1038/s41419-022-05280-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519755/
https://www.ncbi.nlm.nih.gov/pubmed/36171192
http://dx.doi.org/10.1038/s41419-022-05280-z

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