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Loss of SNAI1 induces cellular plasticity in invasive triple-negative breast cancer cells

The transcription factor SNAI1 mediates epithelial-mesenchymal transition, fibroblast activation and controls inter-tissue migration. High SNAI1 expression characterizes metastatic triple-negative breast carcinomas, and its knockout by CRISPR/Cas9 uncovered an epithelio-mesenchymal phenotype accompa...

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Detalles Bibliográficos
Autores principales:	Tsirigoti, Chrysoula, Ali, Mohamad Moustafa, Maturi, Varun, Heldin, Carl-Henrik, Moustakas, Aristidis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519755/ https://www.ncbi.nlm.nih.gov/pubmed/36171192 http://dx.doi.org/10.1038/s41419-022-05280-z

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