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Influenza A virus NS1 protein represses antiviral immune response by hijacking NF-κB to mediate transcription of type III IFN

BACKGROUND: Non-structural protein 1 (NS1), one of the viral proteins of influenza A viruses (IAVs), plays a crucial role in evading host antiviral immune response. It is known that the IAV NS1 protein regulates the antiviral genes response mainly through several different molecular mechanisms in cy...

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Detalles Bibliográficos
Autores principales: Lee, Meng-Chang, Yu, Cheng-Ping, Chen, Xing-Hong, Liu, Ming-Tsan, Yang, Ji-Rong, Chen, An-Yu, Huang, Chih-Heng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519859/
https://www.ncbi.nlm.nih.gov/pubmed/36189352
http://dx.doi.org/10.3389/fcimb.2022.998584