Synthesis, biological evaluation, and molecular modeling studies of new benzoxazole derivatives as PARP-2 inhibitors targeting breast cancer

Many benzoxazole-based and similar scaffolds were reported to have wide-range of anticancer activities. In this study, four series of benzoxazole derivatives were designed by combining benzoxazole scaffold with different amines via a reversed phenyl amide linker to produce the compounds of series A,...

Descripción completa

Detalles Bibliográficos
Autores principales: El-Ghobashy, Nadeen M., El-Sayed, Selwan M., Shehata, Ihsan A., El-Ashmawy, Mahmoud B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519869/
https://www.ncbi.nlm.nih.gov/pubmed/36171229
http://dx.doi.org/10.1038/s41598-022-20260-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519869/
https://www.ncbi.nlm.nih.gov/pubmed/36171229
http://dx.doi.org/10.1038/s41598-022-20260-1

Ejemplares similares