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Comprehensive assessment of actionable genomic alterations in primary colorectal carcinoma using targeted next-generation sequencing

BACKGROUND: The clinical utility of comprehensive genomic profiling (CGP) for guiding treatment has gradually become the standard-of-care procedure for colorectal carcinoma (CRC). Here, we comprehensively assess emerging targeted therapy biomarkers using CGP in primary CRC. METHODS: A total of 575 p...

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Detalles Bibliográficos
Autores principales: Jan, Yi-Hua, Tan, Kien Thiam, Chen, Shu-Jen, Yip, Timothy Tak Chun, Lu, Cu tai, Lam, Alfred King-yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519871/
https://www.ncbi.nlm.nih.gov/pubmed/35842545
http://dx.doi.org/10.1038/s41416-022-01913-4