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In vivo self-assembled siRNA as a modality for combination therapy of ulcerative colitis

Given the complex nature of ulcerative colitis, combination therapy targeting multiple pathogenic genes and pathways of ulcerative colitis may be required. Unfortunately, current therapeutic strategies are usually based on independent chemical compounds or monoclonal antibodies, and the full potenti...

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Detalles Bibliográficos
Autores principales: Zhou, Xinyan, Yu, Mengchao, Ma, Luzhen, Fu, Jinyu, Guo, Jingwei, Lei, Jieqiong, Fu, Zheng, Fu, Yong, Zhang, Qipeng, Zhang, Chen-Yu, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519883/
https://www.ncbi.nlm.nih.gov/pubmed/36171212
http://dx.doi.org/10.1038/s41467-022-33436-0