Mycobacterium tuberculosis KasA as a drug target: Structure-based inhibitor design

Recent studies have reported the β-ketoacyl-acyl carrier protein KasA as a druggable target for Mycobacterium tuberculosis. This review summarizes the current status of major classes of KasA inhibitors with an emphasis on significant contributions from structure-based design methods leveraging X-ray...

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Detalles Bibliográficos
Autores principales: Rudraraju, Reshma S., Daher, Samer S., Gallardo-Macias, Ricardo, Wang, Xin, Neiditch, Matthew B., Freundlich, Joel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519891/
https://www.ncbi.nlm.nih.gov/pubmed/36189349
http://dx.doi.org/10.3389/fcimb.2022.1008213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519891/
https://www.ncbi.nlm.nih.gov/pubmed/36189349
http://dx.doi.org/10.3389/fcimb.2022.1008213

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