Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics

The molecular evolution of cytochromes P450 and associated redox-driven oxidative catalysis remains a mystery in biology. It is widely believed that sterol 14α-demethylase (CYP51), an essential enzyme of sterol biosynthesis, is the ancestor of the whole P450 superfamily given its conservation across...

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Detalles Bibliográficos
Autores principales: Hargrove, Tatiana Y., Lamb, David C., Smith, Jarrod A., Wawrzak, Zdzislaw, Kelly, Steven L., Lepesheva, Galina I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519919/
https://www.ncbi.nlm.nih.gov/pubmed/36171457
http://dx.doi.org/10.1038/s41598-022-20671-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519919/
https://www.ncbi.nlm.nih.gov/pubmed/36171457
http://dx.doi.org/10.1038/s41598-022-20671-0

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