Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer

BACKGROUND: Ovarian cancer patients frequently develop chemotherapy resistance, limiting treatment options. We have previously shown that individuality in fibroblast growth factor 1 (FGF1) expression influences survival and chemotherapy response. METHODS: We used MTT assays to assess chemosensitivit...

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Detalles Bibliográficos
Autores principales: Nicholson, Hugh A., Sawers, Lynne, Clarke, Rosemary G., Hiom, Kevin J., Ferguson, Michelle J., Smith, Gillian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519926/
https://www.ncbi.nlm.nih.gov/pubmed/35778553
http://dx.doi.org/10.1038/s41416-022-01899-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519926/
https://www.ncbi.nlm.nih.gov/pubmed/35778553
http://dx.doi.org/10.1038/s41416-022-01899-z

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