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Fibroblast growth factor signalling influences homologous recombination-mediated DNA damage repair to promote drug resistance in ovarian cancer

BACKGROUND: Ovarian cancer patients frequently develop chemotherapy resistance, limiting treatment options. We have previously shown that individuality in fibroblast growth factor 1 (FGF1) expression influences survival and chemotherapy response. METHODS: We used MTT assays to assess chemosensitivit...

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Detalles Bibliográficos
Autores principales:	Nicholson, Hugh A., Sawers, Lynne, Clarke, Rosemary G., Hiom, Kevin J., Ferguson, Michelle J., Smith, Gillian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519926/ https://www.ncbi.nlm.nih.gov/pubmed/35778553 http://dx.doi.org/10.1038/s41416-022-01899-z

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