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A key role of miR-132-5p in the prefrontal cortex for persistent prophylactic actions of (R)-ketamine in mice

(R,S)-ketamine is known to elicit persistent prophylactic effects in rodent models of depression. However, the precise molecular mechanisms underlying its action remain elusive. Using RNA-sequencing analysis, we searched for novel molecular target(s) that contribute to the prophylactic effects of (R...

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Detalles Bibliográficos
Autores principales: Ma, Li, Wang, Long, Chang, Lijia, Shan, Jiajing, Qu, Youge, Wang, Xingming, Wan, Xiayun, Fujita, Yuko, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9519951/
https://www.ncbi.nlm.nih.gov/pubmed/36171191
http://dx.doi.org/10.1038/s41398-022-02192-6