Glu289 residue in the pore-forming motif of Vibrio cholerae cytolysin is important for efficient β-barrel pore formation

Vibrio cholerae cytolysin (VCC) is a potent membrane-damaging β-barrel pore-forming toxin. Upon binding to the target membranes, VCC monomers first assemble into oligomeric prepore intermediates and subsequently transform into transmembrane β-barrel pores. VCC harbors a designated pore-forming motif...

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Detalles Bibliográficos
Autores principales: Mondal, Anish Kumar, Sengupta, Nayanika, Singh, Mahendra, Biswas, Rupam, Lata, Kusum, Lahiri, Indrajit, Dutta, Somnath, Chattopadhyay, Kausik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520032/
https://www.ncbi.nlm.nih.gov/pubmed/36055404
http://dx.doi.org/10.1016/j.jbc.2022.102441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520032/
https://www.ncbi.nlm.nih.gov/pubmed/36055404
http://dx.doi.org/10.1016/j.jbc.2022.102441

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