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Structures of Streptococcus pyogenes class A sortase in complex with substrate and product mimics provide key details of target recognition

The cell wall is a critical extracellular barrier for bacteria and many other organisms. In bacteria, this structural layer consists of peptidoglycan, which maintains cell shape and structural integrity and provides a scaffold for displaying various protein factors. To attach proteins to the cell wa...

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Detalles Bibliográficos
Autores principales: Johnson, D. Alex, Piper, Isabel M., Vogel, Brandon A., Jackson, Sophie N., Svendsen, Justin E., Kodama, Hanna M., Lee, Darren E., Lindblom, Katy M., McCarty, James, Antos, John M., Amacher, Jeanine F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9520033/
https://www.ncbi.nlm.nih.gov/pubmed/36055407
http://dx.doi.org/10.1016/j.jbc.2022.102446